| Edwardsville to Carrollwood (Florida) | 857.00 mi (1,379.20 km) |
| Edwardsville to Carson (California) | 1,603.80 mi (2,581.07 km) |
| Edwardsville to Carson City (Nevada) | 1,591.60 mi (2,561.43 km) |
| Edwardsville to Carteret (New Jersey) | 845.83 mi (1,361.22 km) |
| Edwardsville to Cartersville (Georgia) | 430.27 mi (692.45 km) |
| Edwardsville to Carthage (Missouri) | 261.92 mi (421.52 km) |
| Edwardsville to Cary (Illinois) | 253.36 mi (407.74 km) |
| Edwardsville to Cary (North Carolina) | 647.67 mi (1,042.32 km) |
| Edwardsville to Casa de Oro-Mount Helix (California) | 1,562.33 mi (2,514.33 km) |
| Edwardsville to Casa Grande (Arizona) | 1,281.78 mi (2,062.82 km) |
| Edwardsville to Casas Adobes (Arizona) | 1,259.25 mi (2,026.56 km) |
| Edwardsville to Cascades (Virginia) | 677.02 mi (1,089.56 km) |
| Edwardsville to Casper (Wyoming) | 897.01 mi (1,443.60 km) |
| Edwardsville to Casselberry (Florida) | 858.01 mi (1,380.83 km) |
| Edwardsville to Castaic (California) | 1,608.93 mi (2,589.33 km) |
