| Edwardsville to Cadillac (Michigan) | 444.89 mi (715.98 km) |
| Edwardsville to Caguas (Puerto Rico) | 2,020.37 mi (3,251.47 km) |
| Edwardsville to Cahokia (Illinois) | 18.80 mi (30.26 km) |
| Edwardsville to Calabasas (California) | 1,618.86 mi (2,605.31 km) |
| Edwardsville to Caldwell (Idaho) | 1,419.50 mi (2,284.46 km) |
| Edwardsville to Caledonia (Wisconsin) | 298.00 mi (479.59 km) |
| Edwardsville to Calera (Alabama) | 431.41 mi (694.29 km) |
| Edwardsville to Calexico (California) | 1,485.85 mi (2,391.25 km) |
| Edwardsville to Calhoun (Georgia) | 408.10 mi (656.78 km) |
| Edwardsville to California (Maryland) | 729.27 mi (1,173.64 km) |
| Edwardsville to California City (California) | 1,553.35 mi (2,499.88 km) |
| Edwardsville to Callaway (Florida) | 649.00 mi (1,044.46 km) |
| Edwardsville to Calumet City (Illinois) | 233.50 mi (375.78 km) |
| Edwardsville to Calverton (Maryland) | 700.50 mi (1,127.34 km) |
| Edwardsville to Camano (Washington) | 1,736.86 mi (2,795.21 km) |
