| Edwardsville to Anoka (Minnesota) | 476.46 mi (766.80 km) |
| Edwardsville to Ansonia (Connecticut) | 910.23 mi (1,464.88 km) |
| Edwardsville to Antelope (California) | 1,682.06 mi (2,707.02 km) |
| Edwardsville to Anthem (Arizona) | 1,274.64 mi (2,051.34 km) |
| Edwardsville to Antioch (California) | 1,714.92 mi (2,759.89 km) |
| Edwardsville to Antioch (Illinois) | 273.49 mi (440.13 km) |
| Edwardsville to Apache Junction (Arizona) | 1,255.93 mi (2,021.22 km) |
| Edwardsville to Apex (North Carolina) | 646.35 mi (1,040.20 km) |
| Edwardsville to Apollo Beach (Florida) | 878.33 mi (1,413.53 km) |
| Edwardsville to Apopka (Florida) | 848.84 mi (1,366.07 km) |
| Edwardsville to Apple Valley (California) | 1,531.28 mi (2,464.35 km) |
| Edwardsville to Apple Valley (Minnesota) | 443.32 mi (713.46 km) |
| Edwardsville to Appleton (Wisconsin) | 387.92 mi (624.29 km) |
| Edwardsville to Arbutus (Maryland) | 713.75 mi (1,148.68 km) |
| Edwardsville to Arcadia (California) | 1,584.97 mi (2,550.75 km) |
