| Edwardsville to Anderson (California) | 1,713.67 mi (2,757.89 km) |
| Edwardsville to Anderson (Indiana) | 246.20 mi (396.22 km) |
| Edwardsville to Anderson (South Carolina) | 502.30 mi (808.38 km) |
| Edwardsville to Anderson Creek (North Carolina) | 654.80 mi (1,053.79 km) |
| Edwardsville to Andover (Kansas) | 395.22 mi (636.05 km) |
| Edwardsville to Andover (Minnesota) | 478.32 mi (769.77 km) |
| Edwardsville to Andrews (Texas) | 834.69 mi (1,343.31 km) |
| Edwardsville to Angleton (Texas) | 733.79 mi (1,180.92 km) |
| Edwardsville to Ankeny (Iowa) | 278.36 mi (447.97 km) |
| Edwardsville to Ann Arbor (Michigan) | 407.09 mi (655.15 km) |
| Edwardsville to Anna (Texas) | 524.96 mi (844.84 km) |
| Edwardsville to Annandale (Virginia) | 688.10 mi (1,107.39 km) |
| Edwardsville to Annapolis (Maryland) | 724.62 mi (1,166.16 km) |
| Edwardsville to Annapolis Neck (Maryland) | 725.00 mi (1,166.78 km) |
| Edwardsville to Anniston (Alabama) | 423.33 mi (681.28 km) |
