| Edwardsville to Abilene (Texas) | 700.47 mi (1,127.30 km) |
| Edwardsville to Accokeek (Maryland) | 699.32 mi (1,125.45 km) |
| Edwardsville to Acworth (Georgia) | 440.73 mi (709.29 km) |
| Edwardsville to Ada (Oklahoma) | 462.45 mi (744.24 km) |
| Edwardsville to Addison (Illinois) | 240.60 mi (387.20 km) |
| Edwardsville to Addison (Texas) | 555.92 mi (894.66 km) |
| Edwardsville to Adelanto (California) | 1,542.55 mi (2,482.49 km) |
| Edwardsville to Adelphi (Maryland) | 699.82 mi (1,126.25 km) |
| Edwardsville to Adrian (Michigan) | 379.35 mi (610.51 km) |
| Edwardsville to Affton (Missouri) | 24.79 mi (39.90 km) |
| Edwardsville to Agoura Hills (California) | 1,623.50 mi (2,612.76 km) |
| Edwardsville to Aguadilla (Puerto Rico) | 1,962.51 mi (3,158.35 km) |
| Edwardsville to Aiken (South Carolina) | 586.50 mi (943.88 km) |
| Edwardsville to Akron (Ohio) | 475.28 mi (764.88 km) |
| Edwardsville to Alabaster (Alabama) | 423.63 mi (681.77 km) |
