| Edwardsville to Scarborough | 4,090.92 mi (6,583.69 km) |
| Edwardsville to Scartho | 4,123.97 mi (6,636.89 km) |
| Edwardsville to Scunthorpe | 4,102.07 mi (6,601.64 km) |
| Edwardsville to Seacombe | 4,017.88 mi (6,466.15 km) |
| Edwardsville to Seacroft | 4,065.01 mi (6,542.00 km) |
| Edwardsville to Seaford | 4,215.90 mi (6,784.84 km) |
| Edwardsville to Seaham | 4,040.62 mi (6,502.75 km) |
| Edwardsville to Sedgley | 4,076.84 mi (6,561.04 km) |
| Edwardsville to Selby | 4,080.63 mi (6,567.14 km) |
| Edwardsville to Selsey | 4,182.25 mi (6,730.69 km) |
| Edwardsville to Selston | 4,092.68 mi (6,586.53 km) |
| Edwardsville to Sevenoaks | 4,203.41 mi (6,764.73 km) |
| Edwardsville to Shanklin | 4,170.27 mi (6,711.40 km) |
| Edwardsville to Sheerness | 4,220.33 mi (6,791.97 km) |
| Edwardsville to Sheffield | 4,077.28 mi (6,561.75 km) |
