| Edwardsville to Santarem | 4,202.24 mi (6,762.86 km) |
| Edwardsville to Santiago do Cacem | 4,241.52 mi (6,826.07 km) |
| Edwardsville to Santo Andre | 4,238.03 mi (6,820.46 km) |
| Edwardsville to Santo Tirso | 4,145.32 mi (6,671.26 km) |
| Edwardsville to Sao Bras de Alportel | 4,309.68 mi (6,935.75 km) |
| Edwardsville to Sao Felix da Marinha | 4,147.53 mi (6,674.80 km) |
| Edwardsville to Sao Joao da Madeira | 4,158.07 mi (6,691.77 km) |
| Edwardsville to Sao Joao de Ver | 4,153.39 mi (6,684.24 km) |
| Edwardsville to Sao Mamede de Infesta | 4,143.36 mi (6,668.09 km) |
| Edwardsville to Sao Pedro do Sul | 4,182.35 mi (6,730.84 km) |
| Edwardsville to Satao | 4,198.35 mi (6,756.58 km) |
| Edwardsville to Seia | 4,209.82 mi (6,775.05 km) |
| Edwardsville to Senhora da Hora | 4,141.44 mi (6,665.00 km) |
| Edwardsville to Serpa | 4,296.43 mi (6,914.44 km) |
| Edwardsville to Serta | 4,211.42 mi (6,777.63 km) |
