| Edwardsville to Entroncamento | 4,205.00 mi (6,767.30 km) |
| Edwardsville to Ericeira | 4,176.39 mi (6,721.26 km) |
| Edwardsville to Ermezinde | 4,145.14 mi (6,670.95 km) |
| Edwardsville to Esmoriz | 4,149.84 mi (6,678.52 km) |
| Edwardsville to Espinho | 4,147.50 mi (6,674.75 km) |
| Edwardsville to Esposende | 4,124.44 mi (6,637.65 km) |
| Edwardsville to Estarreja | 4,159.13 mi (6,693.47 km) |
| Edwardsville to Estoril | 4,185.68 mi (6,736.20 km) |
| Edwardsville to Estremoz | 4,266.92 mi (6,866.94 km) |
| Edwardsville to Evora | 4,261.35 mi (6,857.98 km) |
| Edwardsville to Fafe | 4,155.48 mi (6,687.61 km) |
| Edwardsville to Falagueira | 4,192.09 mi (6,746.52 km) |
| Edwardsville to Famalicao | 4,140.39 mi (6,663.32 km) |
| Edwardsville to Fanzeres | 4,147.49 mi (6,674.75 km) |
| Edwardsville to Faro | 4,311.73 mi (6,939.07 km) |
