| Edwardsville to Savignano sul Rubicone | 4,946.19 mi (7,960.13 km) |
| Edwardsville to Savona | 4,779.67 mi (7,692.14 km) |
| Edwardsville to Scafati | 5,172.96 mi (8,325.08 km) |
| Edwardsville to Scalea | 5,265.91 mi (8,474.67 km) |
| Edwardsville to Scandiano | 4,857.57 mi (7,817.50 km) |
| Edwardsville to Scandicci | 4,911.61 mi (7,904.47 km) |
| Edwardsville to Schio | 4,839.06 mi (7,787.71 km) |
| Edwardsville to Sciacca | 5,252.48 mi (8,453.05 km) |
| Edwardsville to Scicli | 5,352.75 mi (8,614.42 km) |
| Edwardsville to Scordia | 5,336.72 mi (8,588.62 km) |
| Edwardsville to Scorze | 4,874.19 mi (7,844.25 km) |
| Edwardsville to Sedico | 4,851.72 mi (7,808.09 km) |
| Edwardsville to Sedriano | 4,753.44 mi (7,649.91 km) |
| Edwardsville to Segni | 5,071.63 mi (8,162.00 km) |
| Edwardsville to Segrate | 4,766.30 mi (7,670.63 km) |
