| Edwardsville to Santa Venerina | 5,331.88 mi (8,580.83 km) |
| Edwardsville to Santeramo in Colle | 5,261.85 mi (8,468.12 km) |
| Edwardsville to Santo Stefano di Magra | 4,843.68 mi (7,795.15 km) |
| Edwardsville to Santo Stino di Livenza | 4,889.98 mi (7,869.67 km) |
| Edwardsville to Sarezzo | 4,795.96 mi (7,718.36 km) |
| Edwardsville to Sarno | 5,173.98 mi (8,326.71 km) |
| Edwardsville to Saronno | 4,750.70 mi (7,645.52 km) |
| Edwardsville to Sarzana | 4,847.45 mi (7,801.21 km) |
| Edwardsville to Sassari | 4,924.83 mi (7,925.75 km) |
| Edwardsville to Sasso Marconi | 4,887.82 mi (7,866.19 km) |
| Edwardsville to Sassuolo | 4,863.12 mi (7,826.44 km) |
| Edwardsville to Sava | 5,311.75 mi (8,548.43 km) |
| Edwardsville to Saviano | 5,165.58 mi (8,313.20 km) |
| Edwardsville to Savigliano | 4,731.82 mi (7,615.13 km) |
| Edwardsville to Savignano sul Panaro | 4,875.79 mi (7,846.82 km) |
