| Eastpointe to Scottsboro (Alabama) | 565.74 mi (910.46 km) |
| Eastpointe to Scottsdale (Arizona) | 1,675.66 mi (2,696.72 km) |
| Eastpointe to Scranton (Pennsylvania) | 381.23 mi (613.53 km) |
| Eastpointe to Seabrook (Maryland) | 399.68 mi (643.23 km) |
| Eastpointe to Seabrook (Texas) | 1,115.00 mi (1,794.41 km) |
| Eastpointe to Seaford (New York) | 503.95 mi (811.03 km) |
| Eastpointe to Seagoville (Texas) | 1,004.87 mi (1,617.18 km) |
| Eastpointe to Seal Beach (California) | 1,986.05 mi (3,196.23 km) |
| Eastpointe to Searcy (Arkansas) | 686.82 mi (1,105.32 km) |
| Eastpointe to Seaside (California) | 2,091.27 mi (3,365.58 km) |
| Eastpointe to SeaTac (Washington) | 1,933.27 mi (3,111.30 km) |
| Eastpointe to Seattle (Washington) | 1,933.56 mi (3,111.76 km) |
| Eastpointe to Sebastian (Florida) | 1,023.91 mi (1,647.83 km) |
| Eastpointe to Sebring (Florida) | 1,039.01 mi (1,672.13 km) |
| Eastpointe to Secaucus (New Jersey) | 472.94 mi (761.13 km) |
