| Eastpointe to Orangevale (California) | 2,008.29 mi (3,232.03 km) |
| Eastpointe to Orchards (Washington) | 1,957.24 mi (3,149.87 km) |
| Eastpointe to Orcutt (California) | 2,070.57 mi (3,332.26 km) |
| Eastpointe to Oregon (Ohio) | 61.48 mi (98.94 km) |
| Eastpointe to Oregon (Wisconsin) | 328.64 mi (528.90 km) |
| Eastpointe to Oregon City (Oregon) | 1,963.61 mi (3,160.13 km) |
| Eastpointe to Orem (Utah) | 1,490.95 mi (2,399.45 km) |
| Eastpointe to Orinda (California) | 2,076.55 mi (3,341.88 km) |
| Eastpointe to Orland Park (Illinois) | 259.10 mi (416.98 km) |
| Eastpointe to Orlando (Florida) | 970.68 mi (1,562.16 km) |
| Eastpointe to Ormond Beach (Florida) | 915.54 mi (1,473.42 km) |
| Eastpointe to Oro Valley (Arizona) | 1,676.82 mi (2,698.58 km) |
| Eastpointe to Oroville (California) | 2,007.20 mi (3,230.27 km) |
| Eastpointe to Oshkosh (Wisconsin) | 302.35 mi (486.58 km) |
| Eastpointe to Oskaloosa (Iowa) | 504.97 mi (812.67 km) |
