| East Patchogue to Southern Pines (North Carolina) | 520.12 mi (837.05 km) |
| East Patchogue to Southfield (Michigan) | 543.45 mi (874.60 km) |
| East Patchogue to Southgate (Michigan) | 538.02 mi (865.86 km) |
| East Patchogue to Southlake (Texas) | 1,435.12 mi (2,309.60 km) |
| East Patchogue to Spanaway (Washington) | 2,456.46 mi (3,953.29 km) |
| East Patchogue to Spanish Fork (Utah) | 2,016.76 mi (3,245.66 km) |
| East Patchogue to Spanish Lake (Missouri) | 923.34 mi (1,485.97 km) |
| East Patchogue to Spanish Springs (Nevada) | 2,435.02 mi (3,918.79 km) |
| East Patchogue to Sparks (Nevada) | 2,439.11 mi (3,925.36 km) |
| East Patchogue to Spartanburg (South Carolina) | 631.91 mi (1,016.97 km) |
| East Patchogue to Spearfish (South Dakota) | 1,578.71 mi (2,540.68 km) |
| East Patchogue to Speedway (Indiana) | 701.83 mi (1,129.49 km) |
| East Patchogue to Spencer (Iowa) | 1,147.50 mi (1,846.73 km) |
| East Patchogue to Spokane (Washington) | 2,220.13 mi (3,572.96 km) |
| East Patchogue to Spokane Valley (Washington) | 2,210.95 mi (3,558.18 km) |
