| East Niles to Scottsboro (Alabama) | 1,852.50 mi (2,981.31 km) |
| East Niles to Scottsdale (Arizona) | 418.07 mi (672.82 km) |
| East Niles to Scranton (Pennsylvania) | 2,354.65 mi (3,789.45 km) |
| East Niles to Seabrook (Maryland) | 2,309.08 mi (3,716.11 km) |
| East Niles to Seabrook (Texas) | 1,445.36 mi (2,326.08 km) |
| East Niles to Seaford (New York) | 2,472.15 mi (3,978.54 km) |
| East Niles to Seagoville (Texas) | 1,292.44 mi (2,079.98 km) |
| East Niles to Seal Beach (California) | 121.58 mi (195.67 km) |
| East Niles to Searcy (Arkansas) | 1,528.14 mi (2,459.31 km) |
| East Niles to Seaside (California) | 183.68 mi (295.60 km) |
| East Niles to SeaTac (Washington) | 852.30 mi (1,371.64 km) |
| East Niles to Seattle (Washington) | 864.47 mi (1,391.23 km) |
| East Niles to Sebastian (Florida) | 2,307.51 mi (3,713.59 km) |
| East Niles to Sebring (Florida) | 2,261.16 mi (3,638.99 km) |
| East Niles to Secaucus (New Jersey) | 2,441.44 mi (3,929.12 km) |
