| East Niles to Olympia Heights (Florida) | 2,374.14 mi (3,820.80 km) |
| East Niles to Omaha (Nebraska) | 1,300.44 mi (2,092.85 km) |
| East Niles to On Top of the World Designated Place (Florida) | 2,171.60 mi (3,494.85 km) |
| East Niles to Onalaska (Wisconsin) | 1,578.63 mi (2,540.55 km) |
| East Niles to Oneida (New York) | 2,348.74 mi (3,779.94 km) |
| East Niles to Oneonta (New York) | 2,380.73 mi (3,831.42 km) |
| East Niles to Ontario (California) | 118.41 mi (190.55 km) |
| East Niles to Ontario (Oregon) | 607.02 mi (976.90 km) |
| East Niles to Opa-locka (Florida) | 2,373.59 mi (3,819.92 km) |
| East Niles to Opelika (Alabama) | 1,921.11 mi (3,091.73 km) |
| East Niles to Opelousas (Louisiana) | 1,586.64 mi (2,553.45 km) |
| East Niles to Orange (California) | 124.92 mi (201.04 km) |
| East Niles to Orange (Texas) | 1,501.98 mi (2,417.21 km) |
| East Niles to Orange City (Florida) | 2,232.12 mi (3,592.25 km) |
| East Niles to Orangeburg (South Carolina) | 2,159.28 mi (3,475.03 km) |
