| East Lansing to Olympia Heights (Florida) | 1,199.42 mi (1,930.28 km) |
| East Lansing to Omaha (Nebraska) | 602.29 mi (969.29 km) |
| East Lansing to On Top of the World Designated Place (Florida) | 950.47 mi (1,529.63 km) |
| East Lansing to Onalaska (Wisconsin) | 346.96 mi (558.37 km) |
| East Lansing to Oneida (New York) | 446.77 mi (719.00 km) |
| East Lansing to Oneonta (New York) | 479.11 mi (771.05 km) |
| East Lansing to Ontario (California) | 1,877.86 mi (3,022.12 km) |
| East Lansing to Ontario (Oregon) | 1,623.32 mi (2,612.48 km) |
| East Lansing to Opa-locka (Florida) | 1,188.42 mi (1,912.57 km) |
| East Lansing to Opelika (Alabama) | 698.63 mi (1,124.33 km) |
| East Lansing to Opelousas (Louisiana) | 942.75 mi (1,517.21 km) |
| East Lansing to Orange (California) | 1,896.50 mi (3,052.13 km) |
| East Lansing to Orange (Texas) | 1,011.85 mi (1,628.42 km) |
| East Lansing to Orange City (Florida) | 970.83 mi (1,562.40 km) |
| East Lansing to Orangeburg (South Carolina) | 668.82 mi (1,076.37 km) |
