| East Lansing to Enumclaw (Washington) | 1,840.60 mi (2,962.17 km) |
| East Lansing to Ephrata (Pennsylvania) | 464.75 mi (747.95 km) |
| East Lansing to Erie (Colorado) | 1,078.98 mi (1,736.44 km) |
| East Lansing to Erie (Pennsylvania) | 229.07 mi (368.65 km) |
| East Lansing to Erlanger (Kentucky) | 258.26 mi (415.64 km) |
| East Lansing to Escanaba (Michigan) | 244.09 mi (392.83 km) |
| East Lansing to Escondido (California) | 1,881.71 mi (3,028.33 km) |
| East Lansing to Española (New Mexico) | 1,239.00 mi (1,993.97 km) |
| East Lansing to Essex (Maryland) | 481.63 mi (775.11 km) |
| East Lansing to Essex Junction (Vermont) | 580.78 mi (934.68 km) |
| East Lansing to Estelle (Louisiana) | 944.25 mi (1,519.62 km) |
| East Lansing to Estero (Florida) | 1,137.78 mi (1,831.08 km) |
| East Lansing to Euclid (Ohio) | 171.59 mi (276.15 km) |
| East Lansing to Eufaula (Alabama) | 749.71 mi (1,206.54 km) |
| East Lansing to Eugene (Oregon) | 1,923.65 mi (3,095.82 km) |
