| East Islip to Seymour (Tennessee) | 663.58 mi (1,067.93 km) |
| East Islip to Shady Hills (Florida) | 1,002.76 mi (1,613.78 km) |
| East Islip to Shafter (California) | 2,499.14 mi (4,021.98 km) |
| East Islip to Shaker Heights (Ohio) | 438.30 mi (705.38 km) |
| East Islip to Shakopee (Minnesota) | 1,063.65 mi (1,711.78 km) |
| East Islip to Sharon (Pennsylvania) | 382.95 mi (616.30 km) |
| East Islip to Sharonville (Ohio) | 601.71 mi (968.36 km) |
| East Islip to Shasta Lake (California) | 2,541.63 mi (4,090.37 km) |
| East Islip to Shawnee (Kansas) | 1,149.65 mi (1,850.19 km) |
| East Islip to Shawnee (Oklahoma) | 1,341.39 mi (2,158.76 km) |
| East Islip to Sheboygan (Wisconsin) | 771.52 mi (1,241.64 km) |
| East Islip to Shelby (North Carolina) | 589.49 mi (948.69 km) |
| East Islip to Shelbyville (Indiana) | 669.70 mi (1,077.77 km) |
| East Islip to Shelbyville (Kentucky) | 664.88 mi (1,070.03 km) |
| East Islip to Shelbyville (Tennessee) | 805.31 mi (1,296.02 km) |
