| East Islip to Savannah (Georgia) | 746.86 mi (1,201.95 km) |
| East Islip to Sayreville (New Jersey) | 62.29 mi (100.24 km) |
| East Islip to Sayville (New York) | 5.60 mi (9.01 km) |
| East Islip to Scaggsville (Maryland) | 224.36 mi (361.08 km) |
| East Islip to Scarsdale (New York) | 35.86 mi (57.71 km) |
| East Islip to Schaumburg (Illinois) | 776.57 mi (1,249.77 km) |
| East Islip to Schenectady (New York) | 148.48 mi (238.96 km) |
| East Islip to Schererville (Indiana) | 743.27 mi (1,196.17 km) |
| East Islip to Schertz (Texas) | 1,604.27 mi (2,581.83 km) |
| East Islip to Schiller Park (Illinois) | 765.43 mi (1,231.83 km) |
| East Islip to Schofield Barracks (Hawaii) | 5,003.71 mi (8,052.69 km) |
| East Islip to Scotchtown (New York) | 80.40 mi (129.40 km) |
| East Islip to Scottdale (Georgia) | 773.73 mi (1,245.20 km) |
| East Islip to Scotts Valley (California) | 2,604.14 mi (4,190.96 km) |
| East Islip to Scottsbluff (Nebraska) | 1,575.58 mi (2,535.66 km) |
