| East Islip to Santa Rosa (California) | 2,606.35 mi (4,194.52 km) |
| East Islip to Santaquin (Utah) | 2,017.08 mi (3,246.17 km) |
| East Islip to Santee (California) | 2,457.27 mi (3,954.59 km) |
| East Islip to Sapulpa (Oklahoma) | 1,279.25 mi (2,058.75 km) |
| East Islip to Saraland (Alabama) | 1,076.43 mi (1,732.34 km) |
| East Islip to Sarasota (Florida) | 1,067.35 mi (1,717.74 km) |
| East Islip to Sarasota Springs (Florida) | 1,067.25 mi (1,717.58 km) |
| East Islip to Saratoga (California) | 2,599.63 mi (4,183.69 km) |
| East Islip to Saratoga Springs (New York) | 164.62 mi (264.93 km) |
| East Islip to Saratoga Springs (Utah) | 2,017.09 mi (3,246.19 km) |
| East Islip to Sartell (Minnesota) | 1,108.71 mi (1,784.29 km) |
| East Islip to Satellite Beach (Florida) | 963.47 mi (1,550.55 km) |
| East Islip to Sauk Rapids (Minnesota) | 1,105.27 mi (1,778.77 km) |
| East Islip to Sault Ste. Marie (Michigan) | 685.49 mi (1,103.19 km) |
| East Islip to Savage (Minnesota) | 1,057.92 mi (1,702.55 km) |
