| East Islip to Orangevale (California) | 2,525.05 mi (4,063.68 km) |
| East Islip to Orchards (Washington) | 2,468.77 mi (3,973.11 km) |
| East Islip to Orcutt (California) | 2,579.08 mi (4,150.63 km) |
| East Islip to Oregon (Ohio) | 536.21 mi (862.95 km) |
| East Islip to Oregon (Wisconsin) | 846.54 mi (1,362.38 km) |
| East Islip to Oregon City (Oregon) | 2,476.03 mi (3,984.78 km) |
| East Islip to Orem (Utah) | 2,006.79 mi (3,229.62 km) |
| East Islip to Orinda (California) | 2,592.65 mi (4,172.47 km) |
| East Islip to Orland Park (Illinois) | 764.79 mi (1,230.82 km) |
| East Islip to Orlando (Florida) | 963.81 mi (1,551.10 km) |
| East Islip to Ormond Beach (Florida) | 906.76 mi (1,459.29 km) |
| East Islip to Oro Valley (Arizona) | 2,155.89 mi (3,469.56 km) |
| East Islip to Oroville (California) | 2,524.78 mi (4,063.24 km) |
| East Islip to Oshkosh (Wisconsin) | 815.79 mi (1,312.89 km) |
| East Islip to Oskaloosa (Iowa) | 1,012.91 mi (1,630.11 km) |
