| East Islip to Odessa (Texas) | 1,724.98 mi (2,776.08 km) |
| East Islip to Ogden (Utah) | 2,006.25 mi (3,228.75 km) |
| East Islip to Oildale (California) | 2,491.59 mi (4,009.83 km) |
| East Islip to Ojus (Florida) | 1,096.02 mi (1,763.87 km) |
| East Islip to Okemos (Michigan) | 594.46 mi (956.69 km) |
| East Islip to Oklahoma City (Oklahoma) | 1,366.77 mi (2,199.61 km) |
| East Islip to Okmulgee (Oklahoma) | 1,284.76 mi (2,067.61 km) |
| East Islip to Olathe (Kansas) | 1,152.36 mi (1,854.55 km) |
| East Islip to Old Jamestown (Missouri) | 915.65 mi (1,473.59 km) |
| East Islip to Oldsmar (Florida) | 1,027.73 mi (1,653.97 km) |
| East Islip to Olean (New York) | 287.47 mi (462.64 km) |
| East Islip to Olive Branch (Mississippi) | 990.34 mi (1,593.80 km) |
| East Islip to Olivehurst (California) | 2,533.50 mi (4,077.28 km) |
| East Islip to Olney (Maryland) | 232.90 mi (374.82 km) |
| East Islip to Olympia (Washington) | 2,470.89 mi (3,976.51 km) |
