| East Islip to Emeryville (California) | 2,599.51 mi (4,183.51 km) |
| East Islip to Emmaus (Pennsylvania) | 121.88 mi (196.15 km) |
| East Islip to Emporia (Kansas) | 1,232.30 mi (1,983.19 km) |
| East Islip to Encinitas (California) | 2,465.94 mi (3,968.55 km) |
| East Islip to Endicott (New York) | 176.66 mi (284.31 km) |
| East Islip to Endwell (New York) | 175.58 mi (282.57 km) |
| East Islip to Englewood (Colorado) | 1,671.37 mi (2,689.81 km) |
| East Islip to Englewood (Florida) | 1,084.61 mi (1,745.52 km) |
| East Islip to Englewood (New Jersey) | 42.71 mi (68.74 km) |
| East Islip to Englewood (Ohio) | 588.63 mi (947.31 km) |
| East Islip to Enid (Oklahoma) | 1,361.60 mi (2,191.29 km) |
| East Islip to Ennis (Texas) | 1,419.60 mi (2,284.63 km) |
| East Islip to Ensley (Florida) | 1,056.99 mi (1,701.07 km) |
| East Islip to Enterprise (Alabama) | 958.36 mi (1,542.33 km) |
| East Islip to Enterprise (Nevada) | 2,278.71 mi (3,667.23 km) |
