| East Islip to Eau Claire (Wisconsin) | 968.25 mi (1,558.24 km) |
| East Islip to Echelon (New Jersey) | 112.98 mi (181.82 km) |
| East Islip to Eden (North Carolina) | 458.40 mi (737.72 km) |
| East Islip to Eden Prairie (Minnesota) | 1,063.53 mi (1,711.58 km) |
| East Islip to Edgewater (Florida) | 923.30 mi (1,485.91 km) |
| East Islip to Edgewater (New Jersey) | 41.74 mi (67.17 km) |
| East Islip to Edgewood (Maryland) | 187.55 mi (301.83 km) |
| East Islip to Edgewood (Washington) | 2,440.53 mi (3,927.65 km) |
| East Islip to Edina (Minnesota) | 1,059.16 mi (1,704.55 km) |
| East Islip to Edinburg (Texas) | 1,739.08 mi (2,798.78 km) |
| East Islip to Edmond (Oklahoma) | 1,356.39 mi (2,182.89 km) |
| East Islip to Edmonds (Washington) | 2,438.58 mi (3,924.51 km) |
| East Islip to Edwards (Colorado) | 1,755.93 mi (2,825.90 km) |
| East Islip to Edwardsville (Illinois) | 900.87 mi (1,449.82 km) |
| East Islip to Effingham (Illinois) | 820.55 mi (1,320.54 km) |
