| East Islip to Des Plaines (Illinois) | 767.19 mi (1,234.68 km) |
| East Islip to Desert Hot Springs (California) | 2,402.16 mi (3,865.90 km) |
| East Islip to DeSoto (Texas) | 1,421.53 mi (2,287.73 km) |
| East Islip to Destin (Florida) | 1,030.65 mi (1,658.67 km) |
| East Islip to Destrehan (Louisiana) | 1,217.09 mi (1,958.71 km) |
| East Islip to Detroit (Michigan) | 524.98 mi (844.87 km) |
| East Islip to Diamond Bar (California) | 2,467.46 mi (3,970.99 km) |
| East Islip to Diamond Springs (California) | 2,505.47 mi (4,032.17 km) |
| East Islip to Dickinson (North Dakota) | 1,526.19 mi (2,456.16 km) |
| East Islip to Dickinson (Texas) | 1,455.00 mi (2,341.59 km) |
| East Islip to Dickson (Tennessee) | 831.42 mi (1,338.03 km) |
| East Islip to Difficult Run (Virginia) | 254.19 mi (409.08 km) |
| East Islip to Dinuba (California) | 2,481.99 mi (3,994.38 km) |
| East Islip to Discovery Bay (California) | 2,562.34 mi (4,123.68 km) |
| East Islip to Dix Hills (New York) | 9.53 mi (15.34 km) |
