| East Chicago to Superior (Colorado) | 931.98 mi (1,499.88 km) |
| East Chicago to Superior (Wisconsin) | 417.21 mi (671.44 km) |
| East Chicago to Surprise (Arizona) | 1,467.16 mi (2,361.16 km) |
| East Chicago to Susanville (California) | 1,719.59 mi (2,767.42 km) |
| East Chicago to Sussex (Wisconsin) | 110.01 mi (177.04 km) |
| East Chicago to Suwanee (Georgia) | 556.27 mi (895.23 km) |
| East Chicago to Swansea (Illinois) | 252.29 mi (406.01 km) |
| East Chicago to Sweetwater (Florida) | 1,168.36 mi (1,880.29 km) |
| East Chicago to Sweetwater (Texas) | 953.19 mi (1,534.01 km) |
| East Chicago to Sycamore (Illinois) | 67.65 mi (108.87 km) |
| East Chicago to Sylacauga (Alabama) | 588.78 mi (947.56 km) |
| East Chicago to Sylvania (Ohio) | 193.31 mi (311.10 km) |
| East Chicago to Syosset (New York) | 726.47 mi (1,169.14 km) |
| East Chicago to Syracuse (New York) | 585.12 mi (941.66 km) |
| East Chicago to Syracuse (Utah) | 1,272.66 mi (2,048.15 km) |
