| East Chicago to Smyrna (Delaware) | 642.96 mi (1,034.74 km) |
| East Chicago to Smyrna (Georgia) | 561.13 mi (903.05 km) |
| East Chicago to Smyrna (Tennessee) | 395.49 mi (636.48 km) |
| East Chicago to Snellville (Georgia) | 570.20 mi (917.65 km) |
| East Chicago to Snoqualmie (Washington) | 1,724.96 mi (2,776.06 km) |
| East Chicago to Snyder (Texas) | 962.20 mi (1,548.51 km) |
| East Chicago to Socastee (South Carolina) | 717.45 mi (1,154.63 km) |
| East Chicago to Socorro (Texas) | 1,246.70 mi (2,006.38 km) |
| East Chicago to Soddy-Daisy (Tennessee) | 458.36 mi (737.66 km) |
| East Chicago to Solana Beach (California) | 1,732.77 mi (2,788.63 km) |
| East Chicago to Soledad (California) | 1,841.33 mi (2,963.33 km) |
| East Chicago to Solon (Ohio) | 311.61 mi (501.49 km) |
| East Chicago to Somers Point (New Jersey) | 693.40 mi (1,115.92 km) |
| East Chicago to Somerset (Kentucky) | 349.93 mi (563.16 km) |
| East Chicago to Somerset (New Jersey) | 678.59 mi (1,092.08 km) |
