| East Chicago to Silver Firs (Washington) | 1,739.74 mi (2,799.84 km) |
| East Chicago to Silver Spring (Maryland) | 578.73 mi (931.37 km) |
| East Chicago to Silver Springs Shores (Florida) | 918.12 mi (1,477.58 km) |
| East Chicago to Silverdale (Washington) | 1,764.28 mi (2,839.34 km) |
| East Chicago to Silverton (Oregon) | 1,776.41 mi (2,858.85 km) |
| East Chicago to Simi Valley (California) | 1,768.48 mi (2,846.09 km) |
| East Chicago to Simpsonville (South Carolina) | 554.85 mi (892.95 km) |
| East Chicago to Sioux City (Iowa) | 461.81 mi (743.22 km) |
| East Chicago to Sioux Falls (South Dakota) | 489.34 mi (787.51 km) |
| East Chicago to Skokie (Illinois) | 30.64 mi (49.31 km) |
| East Chicago to Sleepy Hollow (New York) | 704.57 mi (1,133.89 km) |
| East Chicago to Slidell (Louisiana) | 795.41 mi (1,280.09 km) |
| East Chicago to Smithfield (North Carolina) | 648.52 mi (1,043.70 km) |
| East Chicago to Smithfield (Utah) | 1,252.32 mi (2,015.42 km) |
| East Chicago to Smithville (Missouri) | 404.97 mi (651.74 km) |
