| Durham to Southern Pines (North Carolina) | 3,816.59 mi (6,142.20 km) |
| Durham to Southfield (Michigan) | 3,605.46 mi (5,802.42 km) |
| Durham to Southgate (Michigan) | 3,616.44 mi (5,820.10 km) |
| Durham to Southlake (Texas) | 4,600.79 mi (7,404.25 km) |
| Durham to Spanaway (Washington) | 4,602.01 mi (7,406.22 km) |
| Durham to Spanish Fork (Utah) | 4,696.92 mi (7,558.97 km) |
| Durham to Spanish Lake (Missouri) | 4,042.13 mi (6,505.19 km) |
| Durham to Spanish Springs (Nevada) | 4,961.40 mi (7,984.61 km) |
| Durham to Sparks (Nevada) | 4,967.59 mi (7,994.56 km) |
| Durham to Spartanburg (South Carolina) | 3,926.49 mi (6,319.07 km) |
| Durham to Spearfish (South Dakota) | 4,212.75 mi (6,779.77 km) |
| Durham to Speedway (Indiana) | 3,846.37 mi (6,190.14 km) |
| Durham to Spencer (Iowa) | 3,995.92 mi (6,430.81 km) |
| Durham to Spokane (Washington) | 4,439.11 mi (7,144.06 km) |
| Durham to Spokane Valley (Washington) | 4,434.04 mi (7,135.90 km) |
