| Duluth to Storm Lake (Iowa) | 322.51 mi (519.03 km) |
| Duluth to Storrs (Connecticut) | 1,038.33 mi (1,671.04 km) |
| Duluth to Stoughton (Wisconsin) | 302.01 mi (486.04 km) |
| Duluth to Stow (Ohio) | 657.05 mi (1,057.42 km) |
| Duluth to Streamwood (Illinois) | 382.20 mi (615.09 km) |
| Duluth to Streator (Illinois) | 423.64 mi (681.78 km) |
| Duluth to Streetsboro (Ohio) | 657.85 mi (1,058.70 km) |
| Duluth to Strongsville (Ohio) | 635.18 mi (1,022.22 km) |
| Duluth to Stuart (Florida) | 1,499.71 mi (2,413.56 km) |
| Duluth to Stuarts Draft (Virginia) | 899.55 mi (1,447.68 km) |
| Duluth to Sturgis (Michigan) | 477.91 mi (769.12 km) |
| Duluth to Suamico (Wisconsin) | 245.81 mi (395.60 km) |
| Duluth to Sudley (Virginia) | 922.73 mi (1,484.99 km) |
| Duluth to Suffern (New York) | 974.15 mi (1,567.74 km) |
| Duluth to Suffolk (Virginia) | 1,056.60 mi (1,700.43 km) |
