| Duluth to Enumclaw (Washington) | 1,398.59 mi (2,250.81 km) |
| Duluth to Ephrata (Pennsylvania) | 918.24 mi (1,477.76 km) |
| Duluth to Erie (Colorado) | 795.77 mi (1,280.67 km) |
| Duluth to Erie (Pennsylvania) | 675.61 mi (1,087.29 km) |
| Duluth to Erlanger (Kentucky) | 658.09 mi (1,059.10 km) |
| Duluth to Escanaba (Michigan) | 251.39 mi (404.57 km) |
| Duluth to Escondido (California) | 1,610.89 mi (2,592.48 km) |
| Duluth to Española (New Mexico) | 1,033.90 mi (1,663.90 km) |
| Duluth to Essex (Maryland) | 943.26 mi (1,518.03 km) |
| Duluth to Essex Junction (Vermont) | 930.26 mi (1,497.10 km) |
| Duluth to Estelle (Louisiana) | 1,174.90 mi (1,890.83 km) |
| Duluth to Estero (Florida) | 1,515.33 mi (2,438.69 km) |
| Duluth to Euclid (Ohio) | 635.74 mi (1,023.12 km) |
| Duluth to Eufaula (Alabama) | 1,091.77 mi (1,757.03 km) |
| Duluth to Eugene (Oregon) | 1,504.25 mi (2,420.85 km) |
