| Duluth to Emeryville (California) | 1,647.27 mi (2,651.03 km) |
| Duluth to Emmaus (Pennsylvania) | 934.39 mi (1,503.75 km) |
| Duluth to Emporia (Kansas) | 613.93 mi (988.03 km) |
| Duluth to Encinitas (California) | 1,622.90 mi (2,611.81 km) |
| Duluth to Endicott (New York) | 854.41 mi (1,375.05 km) |
| Duluth to Endwell (New York) | 855.67 mi (1,377.06 km) |
| Duluth to Englewood (Colorado) | 811.70 mi (1,306.31 km) |
| Duluth to Englewood (Florida) | 1,468.59 mi (2,363.47 km) |
| Duluth to Englewood (New Jersey) | 989.44 mi (1,592.35 km) |
| Duluth to Englewood (Ohio) | 618.25 mi (994.98 km) |
| Duluth to Enid (Oklahoma) | 774.70 mi (1,246.76 km) |
| Duluth to Ennis (Texas) | 1,026.28 mi (1,651.63 km) |
| Duluth to Ensley (Florida) | 1,152.44 mi (1,854.68 km) |
| Duluth to Enterprise (Alabama) | 1,118.55 mi (1,800.14 km) |
| Duluth to Enterprise (Nevada) | 1,401.08 mi (2,254.82 km) |
