| Drexel Heights to Southern Pines (North Carolina) | 1,824.07 mi (2,935.56 km) |
| Drexel Heights to Southfield (Michigan) | 1,675.40 mi (2,696.30 km) |
| Drexel Heights to Southgate (Michigan) | 1,673.01 mi (2,692.46 km) |
| Drexel Heights to Southlake (Texas) | 810.75 mi (1,304.77 km) |
| Drexel Heights to Spanaway (Washington) | 1,194.56 mi (1,922.46 km) |
| Drexel Heights to Spanish Fork (Utah) | 551.30 mi (887.24 km) |
| Drexel Heights to Spanish Lake (Missouri) | 1,255.78 mi (2,020.98 km) |
| Drexel Heights to Spanish Springs (Nevada) | 707.93 mi (1,139.31 km) |
| Drexel Heights to Sparks (Nevada) | 705.71 mi (1,135.72 km) |
| Drexel Heights to Spartanburg (South Carolina) | 1,682.23 mi (2,707.29 km) |
| Drexel Heights to Spearfish (South Dakota) | 937.83 mi (1,509.30 km) |
| Drexel Heights to Speedway (Indiana) | 1,478.04 mi (2,378.68 km) |
| Drexel Heights to Spencer (Iowa) | 1,151.36 mi (1,852.94 km) |
| Drexel Heights to Spokane (Washington) | 1,123.59 mi (1,808.24 km) |
| Drexel Heights to Spokane Valley (Washington) | 1,120.23 mi (1,802.84 km) |
