| Miami (Florida) to Guaynabo | 1,036.22 mi (1,667.64 km) |
| Tampa (Florida) to Guaynabo | 1,229.54 mi (1,978.75 km) |
| Atlanta (Georgia) to Guaynabo | 1,550.73 mi (2,495.65 km) |
| Washington (District of Columbia) to Guaynabo | 1,561.51 mi (2,513.00 km) |
| Baltimore (Maryland) to Guaynabo | 1,576.28 mi (2,536.78 km) |
| Philadelphia (Pennsylvania) to Guaynabo | 1,587.88 mi (2,555.45 km) |
| Brooklyn (New York) to Guaynabo | 1,607.28 mi (2,586.67 km) |
| New York (New York) to Guaynabo | 1,609.74 mi (2,590.63 km) |
| Queens (New York) to Guaynabo | 1,611.22 mi (2,593.00 km) |
| Boston (Massachusetts) to Guaynabo | 1,679.36 mi (2,702.68 km) |
| Detroit (Michigan) to Guaynabo | 1,934.55 mi (3,113.36 km) |
| Houston (Texas) to Guaynabo | 2,000.00 mi (3,218.69 km) |
| St. Louis (Missouri) to Guaynabo | 2,013.69 mi (3,240.72 km) |
| Chicago (Illinois) to Guaynabo | 2,058.31 mi (3,312.52 km) |
| Dallas (Texas) to Guaynabo | 2,142.64 mi (3,448.24 km) |
| Minneapolis (Minnesota) to Guaynabo | 2,410.32 mi (3,879.04 km) |
| Denver (Colorado) to Guaynabo | 2,736.04 mi (4,403.23 km) |
| Phoenix (Arizona) to Guaynabo | 3,014.13 mi (4,850.77 km) |
| Las Vegas (Nevada) to Guaynabo | 3,219.92 mi (5,181.96 km) |
| San Diego (California) to Guaynabo | 3,297.41 mi (5,306.67 km) |
| Riverside (California) to Guaynabo | 3,319.71 mi (5,342.55 km) |
| Los Angeles (California) to Guaynabo | 3,378.51 mi (5,437.18 km) |
| San Francisco (California) to Guaynabo | 3,625.98 mi (5,835.44 km) |
| Portland (Oregon) to Guaynabo | 3,712.33 mi (5,974.42 km) |
| Seattle (Washington) to Guaynabo | 3,726.61 mi (5,997.41 km) |
