| Difficult Run to Wayne (Michigan) | 393.35 mi (633.03 km) |
| Difficult Run to Waynesboro (Pennsylvania) | 60.11 mi (96.74 km) |
| Difficult Run to Waynesboro (Virginia) | 101.92 mi (164.03 km) |
| Difficult Run to Weatherford (Oklahoma) | 1,193.91 mi (1,921.41 km) |
| Difficult Run to Weatherford (Texas) | 1,217.23 mi (1,958.95 km) |
| Difficult Run to Webb City (Missouri) | 938.37 mi (1,510.15 km) |
| Difficult Run to Webster (Texas) | 1,200.83 mi (1,932.54 km) |
| Difficult Run to Webster Groves (Missouri) | 700.70 mi (1,127.66 km) |
| Difficult Run to Weddington (North Carolina) | 326.86 mi (526.02 km) |
| Difficult Run to Weigelstown (Pennsylvania) | 79.78 mi (128.39 km) |
| Difficult Run to Weirton (West Virginia) | 200.34 mi (322.42 km) |
| Difficult Run to Wekiwa Springs (Florida) | 742.60 mi (1,195.11 km) |
| Difficult Run to Welby (Colorado) | 1,470.74 mi (2,366.93 km) |
| Difficult Run to Wellington (Colorado) | 1,467.34 mi (2,361.46 km) |
| Difficult Run to Wellington (Florida) | 863.49 mi (1,389.65 km) |
