| Difficult Run to Vinings (Georgia) | 527.16 mi (848.38 km) |
| Difficult Run to Virginia Beach (Virginia) | 165.84 mi (266.89 km) |
| Difficult Run to Visalia (California) | 2,284.24 mi (3,676.13 km) |
| Difficult Run to Vista (California) | 2,245.04 mi (3,613.04 km) |
| Difficult Run to Wabash (Indiana) | 468.53 mi (754.03 km) |
| Difficult Run to Waco (Texas) | 1,225.87 mi (1,972.84 km) |
| Difficult Run to Waconia (Minnesota) | 937.94 mi (1,509.47 km) |
| Difficult Run to Wade Hampton (South Carolina) | 391.09 mi (629.40 km) |
| Difficult Run to Wadsworth (Ohio) | 274.74 mi (442.15 km) |
| Difficult Run to Waggaman (Louisiana) | 959.09 mi (1,543.51 km) |
| Difficult Run to Wahiawa (Hawaii) | 4,813.22 mi (7,746.13 km) |
| Difficult Run to Waianae (Hawaii) | 4,823.30 mi (7,762.35 km) |
| Difficult Run to Waihee-Waiehu (Hawaii) | 4,756.52 mi (7,654.89 km) |
| Difficult Run to Wailuku (Hawaii) | 4,757.91 mi (7,657.11 km) |
| Difficult Run to Waimalu (Hawaii) | 4,813.19 mi (7,746.09 km) |
