| Difficult Run to South Plainfield (New Jersey) | 193.97 mi (312.16 km) |
| Difficult Run to South Portland (Maine) | 490.71 mi (789.72 km) |
| Difficult Run to South Riding (Virginia) | 8.96 mi (14.42 km) |
| Difficult Run to South River (New Jersey) | 190.52 mi (306.62 km) |
| Difficult Run to South Salt Lake (Utah) | 1,826.42 mi (2,939.33 km) |
| Difficult Run to South San Francisco (California) | 2,421.04 mi (3,896.29 km) |
| Difficult Run to South San Jose Hills (California) | 2,260.28 mi (3,637.57 km) |
| Difficult Run to South Sioux City (Nebraska) | 1,026.39 mi (1,651.82 km) |
| Difficult Run to South St. Paul (Minnesota) | 904.84 mi (1,456.19 km) |
| Difficult Run to South Valley (New Mexico) | 1,634.59 mi (2,630.61 km) |
| Difficult Run to South Venice (Florida) | 869.93 mi (1,400.01 km) |
| Difficult Run to South Whittier (California) | 2,269.00 mi (3,651.60 km) |
| Difficult Run to South Yarmouth (Massachusetts) | 422.24 mi (679.53 km) |
| Difficult Run to Southaven (Mississippi) | 748.35 mi (1,204.35 km) |
| Difficult Run to Southchase (Florida) | 763.08 mi (1,228.06 km) |
