| Difficult Run to Point Pleasant (New Jersey) | 192.67 mi (310.07 km) |
| Difficult Run to Pomona (California) | 2,251.56 mi (3,623.54 km) |
| Difficult Run to Pompano Beach (Florida) | 889.40 mi (1,431.35 km) |
| Difficult Run to Pompton Lakes (New Jersey) | 217.59 mi (350.18 km) |
| Difficult Run to Pompton Plains (New Jersey) | 215.18 mi (346.30 km) |
| Difficult Run to Ponca City (Oklahoma) | 1,084.75 mi (1,745.73 km) |
| Difficult Run to Ponce (Puerto Rico) | 1,580.63 mi (2,543.78 km) |
| Difficult Run to Pontiac (Illinois) | 613.75 mi (987.74 km) |
| Difficult Run to Pontiac (Michigan) | 404.38 mi (650.78 km) |
| Difficult Run to Pooler (Georgia) | 518.44 mi (834.35 km) |
| Difficult Run to Poplar Bluff (Missouri) | 727.50 mi (1,170.80 km) |
| Difficult Run to Poquoson (Virginia) | 133.63 mi (215.06 km) |
| Difficult Run to Port Angeles (Washington) | 2,358.36 mi (3,795.42 km) |
| Difficult Run to Port Arthur (Texas) | 1,130.50 mi (1,819.36 km) |
| Difficult Run to Port Charlotte (Florida) | 867.70 mi (1,396.43 km) |
