| Difficult Run to Pikesville (Maryland) | 48.27 mi (77.69 km) |
| Difficult Run to Pine Bluff (Arkansas) | 875.02 mi (1,408.21 km) |
| Difficult Run to Pine Castle (Florida) | 757.12 mi (1,218.46 km) |
| Difficult Run to Pine Hill (New Jersey) | 140.25 mi (225.70 km) |
| Difficult Run to Pine Hills (Florida) | 751.09 mi (1,208.76 km) |
| Difficult Run to Pinecrest (Florida) | 930.57 mi (1,497.61 km) |
| Difficult Run to Pinehurst (North Carolina) | 281.71 mi (453.36 km) |
| Difficult Run to Pinellas Park (Florida) | 822.85 mi (1,324.26 km) |
| Difficult Run to Pineville (Louisiana) | 996.73 mi (1,604.08 km) |
| Difficult Run to Pineville (North Carolina) | 328.18 mi (528.16 km) |
| Difficult Run to Pinewood (Florida) | 915.71 mi (1,473.70 km) |
| Difficult Run to Piney Green (North Carolina) | 286.87 mi (461.67 km) |
| Difficult Run to Pinole (California) | 2,407.40 mi (3,874.34 km) |
| Difficult Run to Piqua (Ohio) | 377.45 mi (607.45 km) |
| Difficult Run to Pittsburg (California) | 2,386.66 mi (3,840.96 km) |
