| Difficult Run to Petersburg (Virginia) | 117.30 mi (188.77 km) |
| Difficult Run to Pflugerville (Texas) | 1,286.49 mi (2,070.41 km) |
| Difficult Run to Pharr (Texas) | 1,493.26 mi (2,403.16 km) |
| Difficult Run to Phelan (California) | 2,229.72 mi (3,588.39 km) |
| Difficult Run to Phenix City (Alabama) | 619.10 mi (996.35 km) |
| Difficult Run to Philadelphia (Pennsylvania) | 140.64 mi (226.34 km) |
| Difficult Run to Phillipsburg (New Jersey) | 168.71 mi (271.52 km) |
| Difficult Run to Phoenix (Arizona) | 1,958.64 mi (3,152.12 km) |
| Difficult Run to Phoenixville (Pennsylvania) | 129.44 mi (208.31 km) |
| Difficult Run to Picayune (Mississippi) | 906.44 mi (1,458.78 km) |
| Difficult Run to Pickerington (Ohio) | 297.31 mi (478.48 km) |
| Difficult Run to Pico Rivera (California) | 2,270.71 mi (3,654.36 km) |
| Difficult Run to Piedmont (California) | 2,407.85 mi (3,875.06 km) |
| Difficult Run to Pierre (South Dakota) | 1,240.28 mi (1,996.03 km) |
| Difficult Run to Pike Creek Valley (Delaware) | 105.04 mi (169.04 km) |
