| Difficult Run to Naugatuck (Connecticut) | 288.64 mi (464.52 km) |
| Difficult Run to Navarre (Florida) | 797.67 mi (1,283.73 km) |
| Difficult Run to Nederland (Texas) | 1,129.17 mi (1,817.23 km) |
| Difficult Run to Neenah (Wisconsin) | 680.04 mi (1,094.42 km) |
| Difficult Run to Neosho (Missouri) | 938.16 mi (1,509.82 km) |
| Difficult Run to Nesconset (New York) | 259.84 mi (418.17 km) |
| Difficult Run to New Albany (Indiana) | 459.33 mi (739.22 km) |
| Difficult Run to New Albany (Ohio) | 301.12 mi (484.60 km) |
| Difficult Run to New Baltimore (Michigan) | 384.68 mi (619.08 km) |
| Difficult Run to New Baltimore (Virginia) | 22.42 mi (36.09 km) |
| Difficult Run to New Bedford (Massachusetts) | 387.81 mi (624.12 km) |
| Difficult Run to New Berlin (Wisconsin) | 628.48 mi (1,011.44 km) |
| Difficult Run to New Bern (North Carolina) | 263.41 mi (423.92 km) |
| Difficult Run to New Braunfels (Texas) | 1,340.59 mi (2,157.47 km) |
| Difficult Run to New Brighton (Minnesota) | 916.91 mi (1,475.62 km) |
