| Difficult Run to Murray (Kentucky) | 619.47 mi (996.95 km) |
| Difficult Run to Murray (Utah) | 1,826.34 mi (2,939.21 km) |
| Difficult Run to Murraysville (North Carolina) | 319.68 mi (514.48 km) |
| Difficult Run to Murrieta (California) | 2,232.83 mi (3,593.39 km) |
| Difficult Run to Murrysville (Pennsylvania) | 162.62 mi (261.72 km) |
| Difficult Run to Muscatine (Iowa) | 744.23 mi (1,197.72 km) |
| Difficult Run to Muscle Shoals (Alabama) | 636.86 mi (1,024.93 km) |
| Difficult Run to Muscoy (California) | 2,226.98 mi (3,583.98 km) |
| Difficult Run to Muskego (Wisconsin) | 626.17 mi (1,007.73 km) |
| Difficult Run to Muskegon (Michigan) | 551.58 mi (887.68 km) |
| Difficult Run to Muskogee (Oklahoma) | 1,011.52 mi (1,627.88 km) |
| Difficult Run to Mustang (Oklahoma) | 1,145.58 mi (1,843.63 km) |
| Difficult Run to Myers Corner (New York) | 260.45 mi (419.16 km) |
| Difficult Run to Myrtle Beach (South Carolina) | 368.80 mi (593.52 km) |
| Difficult Run to Myrtle Grove (Florida) | 813.76 mi (1,309.63 km) |
