| Difficult Run to Miami Lakes (Florida) | 913.92 mi (1,470.81 km) |
| Difficult Run to Miami Shores (Florida) | 915.48 mi (1,473.32 km) |
| Difficult Run to Miami Springs (Florida) | 919.90 mi (1,480.43 km) |
| Difficult Run to Miamisburg (Ohio) | 373.78 mi (601.54 km) |
| Difficult Run to Michigan City (Indiana) | 537.54 mi (865.09 km) |
| Difficult Run to Middle Island (New York) | 270.58 mi (435.45 km) |
| Difficult Run to Middle River (Maryland) | 58.09 mi (93.48 km) |
| Difficult Run to Middle Valley (Tennessee) | 502.91 mi (809.35 km) |
| Difficult Run to Middleburg (Florida) | 664.05 mi (1,068.69 km) |
| Difficult Run to Middleburg Heights (Ohio) | 291.10 mi (468.48 km) |
| Difficult Run to Middlesex (New Jersey) | 190.31 mi (306.27 km) |
| Difficult Run to Middleton (Wisconsin) | 696.49 mi (1,120.90 km) |
| Difficult Run to Middletown (Connecticut) | 307.65 mi (495.11 km) |
| Difficult Run to Middletown (Delaware) | 94.98 mi (152.85 km) |
| Difficult Run to Middletown (New York) | 233.90 mi (376.43 km) |
