| Difficult Run to Manassas (Virginia) | 12.92 mi (20.79 km) |
| Difficult Run to Manassas Park (Virginia) | 10.40 mi (16.74 km) |
| Difficult Run to Manatí (Puerto Rico) | 1,557.48 mi (2,506.52 km) |
| Difficult Run to Manchester (Missouri) | 708.89 mi (1,140.85 km) |
| Difficult Run to Manchester (New Hampshire) | 417.52 mi (671.93 km) |
| Difficult Run to Manchester (Tennessee) | 535.77 mi (862.25 km) |
| Difficult Run to Manchester (Virginia) | 98.08 mi (157.84 km) |
| Difficult Run to Mandan (North Dakota) | 1,305.26 mi (2,100.61 km) |
| Difficult Run to Mandeville (Louisiana) | 932.09 mi (1,500.05 km) |
| Difficult Run to Mango (Florida) | 805.87 mi (1,296.92 km) |
| Difficult Run to Manhattan (Kansas) | 1,031.64 mi (1,660.26 km) |
| Difficult Run to Manhattan (New York) | 221.50 mi (356.47 km) |
| Difficult Run to Manhattan Beach (California) | 2,289.68 mi (3,684.88 km) |
| Difficult Run to Manitowoc (Wisconsin) | 643.38 mi (1,035.42 km) |
| Difficult Run to Mankato (Minnesota) | 931.82 mi (1,499.62 km) |
