| Difficult Run to Madison (New Jersey) | 201.56 mi (324.38 km) |
| Difficult Run to Madison (Wisconsin) | 690.57 mi (1,111.37 km) |
| Difficult Run to Madison Heights (Michigan) | 390.95 mi (629.17 km) |
| Difficult Run to Madison Heights (Virginia) | 138.56 mi (223.00 km) |
| Difficult Run to Madisonville (Kentucky) | 562.17 mi (904.73 km) |
| Difficult Run to Magalia (California) | 2,340.74 mi (3,767.06 km) |
| Difficult Run to Magna (Utah) | 1,839.46 mi (2,960.33 km) |
| Difficult Run to Magnolia (Arkansas) | 966.26 mi (1,555.04 km) |
| Difficult Run to Maili (Hawaii) | 4,824.73 mi (7,764.65 km) |
| Difficult Run to Maitland (Florida) | 746.20 mi (1,200.90 km) |
| Difficult Run to Makakilo (Hawaii) | 4,822.20 mi (7,760.59 km) |
| Difficult Run to Malden (Massachusetts) | 409.81 mi (659.53 km) |
| Difficult Run to Malibu (California) | 2,306.83 mi (3,712.48 km) |
| Difficult Run to Maltby (Washington) | 2,296.41 mi (3,695.71 km) |
| Difficult Run to Malvern (Arkansas) | 911.72 mi (1,467.27 km) |
