| Difficult Run to Lemay (Missouri) | 697.33 mi (1,122.25 km) |
| Difficult Run to Lemon Grove (California) | 2,245.90 mi (3,614.42 km) |
| Difficult Run to Lemon Hill (California) | 2,354.61 mi (3,789.37 km) |
| Difficult Run to Lemont (Illinois) | 591.86 mi (952.51 km) |
| Difficult Run to Lemoore (California) | 2,309.95 mi (3,717.51 km) |
| Difficult Run to Lenexa (Kansas) | 936.72 mi (1,507.50 km) |
| Difficult Run to Lennox (California) | 2,286.45 mi (3,679.68 km) |
| Difficult Run to Lenoir (North Carolina) | 308.67 mi (496.76 km) |
| Difficult Run to Leominster (Massachusetts) | 384.29 mi (618.46 km) |
| Difficult Run to Leon Valley (Texas) | 1,373.36 mi (2,210.21 km) |
| Difficult Run to Levelland (Texas) | 1,436.68 mi (2,312.11 km) |
| Difficult Run to Levittown (New York) | 239.29 mi (385.09 km) |
| Difficult Run to Levittown (Pennsylvania) | 158.56 mi (255.18 km) |
| Difficult Run to Lewisburg (Tennessee) | 571.53 mi (919.79 km) |
| Difficult Run to Lewiston (Idaho) | 2,057.02 mi (3,310.45 km) |
