| Difficult Run to Land O' Lakes (Florida) | 794.74 mi (1,279.01 km) |
| Difficult Run to Landover (Maryland) | 24.76 mi (39.84 km) |
| Difficult Run to Langley Park (Maryland) | 20.60 mi (33.16 km) |
| Difficult Run to Lanham (Maryland) | 27.46 mi (44.19 km) |
| Difficult Run to Lansdale (Pennsylvania) | 143.80 mi (231.42 km) |
| Difficult Run to Lansdowne (Pennsylvania) | 131.81 mi (212.13 km) |
| Difficult Run to Lansdowne (Virginia) | 14.61 mi (23.51 km) |
| Difficult Run to Lansing (Illinois) | 568.15 mi (914.35 km) |
| Difficult Run to Lansing (Kansas) | 940.22 mi (1,513.14 km) |
| Difficult Run to Lansing (Michigan) | 459.82 mi (740.01 km) |
| Difficult Run to Lantana (Florida) | 865.42 mi (1,392.76 km) |
| Difficult Run to Lantana (Texas) | 1,173.04 mi (1,887.83 km) |
| Difficult Run to Laplace (Louisiana) | 963.15 mi (1,550.04 km) |
| Difficult Run to Laramie (Wyoming) | 1,496.09 mi (2,407.72 km) |
| Difficult Run to Laredo (Texas) | 1,494.21 mi (2,404.69 km) |
