| Difficult Run to La Riviera (California) | 2,348.33 mi (3,779.27 km) |
| Difficult Run to La Vergne (Tennessee) | 542.69 mi (873.38 km) |
| Difficult Run to La Verne (California) | 2,250.47 mi (3,621.79 km) |
| Difficult Run to La Vista (Nebraska) | 1,000.62 mi (1,610.35 km) |
| Difficult Run to Lacey (Washington) | 2,330.51 mi (3,750.60 km) |
| Difficult Run to Lackawanna (New York) | 281.51 mi (453.05 km) |
| Difficult Run to Laconia (New Hampshire) | 443.79 mi (714.22 km) |
| Difficult Run to Ladera Ranch (California) | 2,257.60 mi (3,633.25 km) |
| Difficult Run to Ladson (South Carolina) | 435.35 mi (700.63 km) |
| Difficult Run to Lady Lake (Florida) | 737.48 mi (1,186.85 km) |
| Difficult Run to Lafayette (California) | 2,400.70 mi (3,863.55 km) |
| Difficult Run to Lafayette (Colorado) | 1,476.66 mi (2,376.45 km) |
| Difficult Run to Lafayette (Indiana) | 516.23 mi (830.79 km) |
| Difficult Run to Lafayette (Louisiana) | 1,026.95 mi (1,652.72 km) |
| Difficult Run to LaGrange (Georgia) | 590.95 mi (951.04 km) |
