| Difficult Run to Decatur (Alabama) | 611.52 mi (984.14 km) |
| Difficult Run to Decatur (Georgia) | 524.34 mi (843.84 km) |
| Difficult Run to Decatur (Illinois) | 621.89 mi (1,000.83 km) |
| Difficult Run to Deer Park (New York) | 249.25 mi (401.12 km) |
| Difficult Run to Deer Park (Texas) | 1,194.06 mi (1,921.65 km) |
| Difficult Run to Deerfield (Illinois) | 595.41 mi (958.22 km) |
| Difficult Run to Deerfield Beach (Florida) | 885.13 mi (1,424.47 km) |
| Difficult Run to Defiance (Ohio) | 405.63 mi (652.79 km) |
| Difficult Run to DeForest (Wisconsin) | 691.90 mi (1,113.51 km) |
| Difficult Run to DeKalb (Illinois) | 634.62 mi (1,021.33 km) |
| Difficult Run to Del Aire (California) | 2,287.54 mi (3,681.44 km) |
| Difficult Run to Del City (Oklahoma) | 1,129.18 mi (1,817.23 km) |
| Difficult Run to Del Rio (Texas) | 1,492.26 mi (2,401.55 km) |
| Difficult Run to DeLand (Florida) | 718.75 mi (1,156.72 km) |
| Difficult Run to Delano (California) | 2,292.73 mi (3,689.80 km) |
