| Difficult Run to Chicago Ridge (Illinois) | 582.34 mi (937.19 km) |
| Difficult Run to Chickasha (Oklahoma) | 1,165.29 mi (1,875.35 km) |
| Difficult Run to Chico (California) | 2,352.53 mi (3,786.03 km) |
| Difficult Run to Chicopee (Massachusetts) | 337.63 mi (543.37 km) |
| Difficult Run to Chillicothe (Ohio) | 304.15 mi (489.48 km) |
| Difficult Run to Chillum (Maryland) | 20.28 mi (32.64 km) |
| Difficult Run to Chino (California) | 2,248.16 mi (3,618.07 km) |
| Difficult Run to Chino Hills (California) | 2,252.18 mi (3,624.53 km) |
| Difficult Run to Chino Valley (Arizona) | 1,948.07 mi (3,135.12 km) |
| Difficult Run to Chippewa Falls (Wisconsin) | 832.03 mi (1,339.02 km) |
| Difficult Run to Choctaw (Oklahoma) | 1,119.17 mi (1,801.13 km) |
| Difficult Run to Chowchilla (California) | 2,316.60 mi (3,728.20 km) |
| Difficult Run to Christiansburg (Virginia) | 206.09 mi (331.67 km) |
| Difficult Run to Chubbuck (Idaho) | 1,840.82 mi (2,962.52 km) |
| Difficult Run to Chula Vista (California) | 2,247.59 mi (3,617.15 km) |
